Screening and identification of key biomarkers in breast cancer with brain metastasis: Evidence from bioinformatic analysis

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose. </bold>Breast cancer (BC) has a poor prognosis when brain metastases (BM) occur, and the treatment effect is limited. In this study, we aim to identify representative candidate biomarkers for clinical prognosis of patients with BM and explore the mechanisms underlying the progression of BC.<bold>Methods.</bold> Herein, we examined the<bold> </bold>Microarray datasets (GSE...

Topics

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• Brain Metastases and Treatment
• Brain Neoplasms
• Cluster Analysis
• DNA Copy Number Variations
• Exome Sequencing
• Gene Expression Regulation, Neoplastic
• Lung Cancer Treatments and Mutations
• Radiopharmaceutical Chemistry and Applications

Identifiers and source

Literature Corpus work

623b8eb0-85df-5fdf-a9f5-87406a369d78

DOI

10.21203/rs.3.rs-36118/v1