Article

Genetic screens of RNA binding proteins identify a role for N6-methyladenosine in promoting B cell differentiation

2020-01-01

Abstract excerpt

Post-transcriptional regulation of gene expression is mediated in part by RNA binding proteins (RBPs). Roles for RBPs have emerged in the immune system but remain largely unexplored. My project utilised high-throughput genetic screens to identify roles for RBPs in lymphocytes. Initially, I generated custom sgRNA libraries targeting RBPs to facilitate CRISPR/Cas9 mediated gene knockout screens in either human or mo...

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Literature Corpus work: 37fe2c7c-6067-560b-b432-08dc2711fa78
DOI: 10.17863/cam.63234

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