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Long noncoding RNAs and metabolic memory associated with continued progression of diabetic retinopathy

1 Nov 2024

Abstract excerpt

Progression of diabetic retinopathy resists arrest even after institution of intensive glycemic control, suggesting a "metabolic memory" phenomenon, but the mechanism responsible for this phenomenon is still elusive. Gene expression and biological processes can also be regulated by long noncoding RNAs (LncRNAs), the RNAs with >200 nucleotides and no open reading frame for translation, and several LncRNAs are...

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PMID: 39558680
DOI: 10.1111/1753-0407.70009

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