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Article

Enhanced stability and polyadenylation of select mRNAs support rapid thermogenesis in the brown fat of a hibernator.

eLife - 27 Jan 2015

Grabek Katharine R, Diniz Behn Cecilia, Barsh Gregory S, Hesselberth Jay R, Martin Sandra L

Abstract excerpt

During hibernation, animals cycle between torpor and arousal. These cycles involve dramatic but poorly understood mechanisms of dynamic physiological regulation at the level of gene expression. Each cycle, Brown Adipose Tissue (BAT) drives periodic arousal from torpor by generating essential heat. We applied digital transcriptome analysis to precisely timed samples to identify molecular pathways that underlie the...

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Identifiers

PMID: 25626169
DOI: 10.7554/eLife.04517
PMCID: PMC4383249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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