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Article

Dynamic RNA Regulation in the Brain Underlies Physiological Plasticity in a Hibernating Mammal

18 Jan 2021

Abstract excerpt

Hibernation is a physiological and behavioral phenotype that minimizes energy expenditure. Hibernators cycle between profound depression and rapid hyperactivation of multiple physiological processes, challenging our concept of mammalian homeostasis. How the hibernator orchestrates and survives these extremes while maintaining cell to organismal viability is unknown. Here, we enhance the genome integrity and...

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Identifiers

PMID: 33536943
DOI: 10.3389/fphys.2020.624677

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