Article

The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19

2024-02-28

Abstract excerpt

<h4>Synopsis</h4> <h4>Objectives</h4> Immunocompromised individuals are susceptible to severe COVID-19 and potentially contribute to the emergence of variants with altered pathogenicity due to persistent infection. This study investigated the impact of immunosuppression on SARS-CoV-2 infection in k18-hACE2 mice and the effectiveness of antiviral treatments in this context during the first 7 days of infection. <h...

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Literature Corpus work: 376464e9-b68d-5c8b-9c69-c2a84be40086
DOI: 10.1101/2024.02.27.582110

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