Article

Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice

2022-06-28

Abstract excerpt

<h4>ABSTRACT</h4> As the SARS-CoV-2 pandemic remains uncontrolled owing to the continuous emergence of variants of concern, there is an immediate need to implement the most effective antiviral treatment strategies, especially for risk groups. Here, we evaluated the therapeutic potency of nirmatrelvir, remdesivir, and molnupiravir and their combinations in SARS-CoV-2-infected K18-hACE2 transgenic mice. Systemic tr...

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Literature Corpus work: 9bec2510-1437-5416-b4f2-6a7b17e11e3f
DOI: 10.1101/2022.06.27.497875

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