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Article

Systemic exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the living mouse brain

2024-11-27

Abstract excerpt

Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) causes a systemic infection that affects the central nervous system. We used virus-like particles (VLPs) to explore how exposure to the SARS-CoV-2 proteins affects brain activity patterns in wild-type (WT) mice and in mice that express the wild-type human tau protein (htau mice). VLP exposure elicited dose-dependent changes in corticosterone and distinc...

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Identifiers and source

Literature Corpus work
3744f8d2-033b-5f03-a26e-ba0269b9ffed
DOI
10.1101/2024.11.26.625543
Open publication

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Systemic exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the living mouse brainDOI 10.1101/2024.11.26.625543
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