Article

Natural genetic variation quantitatively regulates heart rate and dimension

2023-09-02

Abstract excerpt

The polygenic contribution to heart development and function along the health-disease continuum remains unresolved. To gain insight into the genetic basis of quantitative cardiac phenotypes, we utilize highly inbred Japanese rice fish models, Oryzias latipes , and Oryzias sakaizumii . Employing automated quantification of embryonic heart rates as core metric, we profiled phenotype variability across five inbred...

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Literature Corpus work: 36d84222-edc8-530e-b022-0e4a5a1a5688
DOI: 10.1101/2023.09.01.555906

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