Article

The clinical and functional effects of <i>TERT</i> variants in myelodysplastic syndrome

2021-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Germline pathogenic TERT variants are associated with short telomeres and an increased risk of developing myelodysplastic syndrome (MDS) among patients with a telomere biology disorder. We identified TERT rare variants in 41 of 1514 MDS patients (2.7%) without a clinical diagnosis of telomere biology disorder who underwent allogeneic transplantation. Patients with TERT rare variants had short...

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Literature Corpus work: 36cf6409-ee6b-5066-9c8f-f560d4a26345
DOI: 10.1101/2021.02.11.430624

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