Article

Beyond Parkinson’s disease: expanding the neurodegenerative spectrum of GBA1- associated disorders

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> Heterozygous variants in the <italic>GBA1</italic> gene represent the most significant genetic risk factor for Parkinson’s disease (PD). Among a larger cohort of 110 individuals with atypical parkinsonism and multisystem phenotypes, we identified nine patients carrying monoallelic pathogenic <italic>GBA1</italic> variants. Clinical and biochemical phenotyping revealed marked heter...

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Literature Corpus work: 36b82635-3973-5d7d-b533-ac43a627378a
DOI: 10.21203/rs.3.rs-10567488/v1

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