Article

The role of drug disposition genes for variability in the pharmacokinetics of antiretroviral drugs

2013-01-01

Abstract excerpt

The failure of highly active antiretroviral therapy may be due to pharmacological factors such as drug transporters and metabolism enzymes. Drug transporters and metabolism enzymes played complementary roles in drug absorption, distribution, metabolism and excretion by biotransformation and counter-transport, particularly in the intestine while nuclear receptors as transcription factors regulate the expression of...

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Literature Corpus work: 3656fc8b-7c27-58ab-bdb9-3f8ef04f1815
DOI: 10.17638/00009075

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