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Article

Real world use of avacopan for ANCA-associated vasculitis. First experiences in Ireland.

2025-09-26

Abstract excerpt

<h4>Background: </h4> Avacopan, a selective complement 5a receptor (C5aR) antagonist, is used for the treatment of severe active granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) in combination with rituximab or cyclophosphamide. By reducing glucocorticoid exposure and associated toxicity, avacopan can improve patient outcomes. This report presents the first clinical experience with avacopan...

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Literature Corpus work
362ed8a7-ce66-5ede-bdcf-d04197da19e8
DOI
10.12688/hrbopenres.14159.1
Open publication

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Real world use of avacopan for ANCA-associated vasculitis. First experiences in Ireland.DOI 10.12688/hrbopenres.14159.1
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