Article

Insights into the Anti-Inflammatory Effects of Soft Tissue Manipulation

2025-09-02

Abstract excerpt

Soft tissue manipulation (STM) is widely used by physical therapists, massage therapists, athletic trainers, and osteopathic physicians to manage musculoskeletal pain, yet its biological mechanisms remain poorly understood. Preclinical studies indicate that STM can alter immune cell behavior in animal models, increasing anti-inflammatory cytokines (IL 4, IL 10) and reducing chemokines such as RANTES/CCL5. Single-c...

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Literature Corpus work: 3600539a-5ba4-5705-832f-ff3f0a779d57
DOI: 10.20944/preprints202509.0158.v1

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