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Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4

2022-12-04

Abstract excerpt

Circular RNAs (circRNAs) are generated by back-splicing and control cellular signaling and phenotypes. Pericytes stabilize the capillary structure and play an important role in the formation and maintenance of new blood vessels. Here, we characterized hypoxia-regulated circRNAs in human pericytes and showed that circPLOD2 is induced by hypoxia and regulates pericyte function. Silencing of circPLOD2 increased peric...

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Literature Corpus work
34ef4d7b-33da-5052-b912-aa3dd0fe9a29
DOI
10.1101/2022.12.04.519017
Open publication

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Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4DOI 10.1101/2022.12.04.519017
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