Article

Invasive cancer and spontaneous regression two weeks after papillomavirus infection

2024-09-07

Abstract excerpt

Development of invasive cancer in mammals is thought to require months or years after initial events such as mutation or viral infection. Rarely, invasive cancers regress spontaneously. We show that cancers can develop and regress on a timescale of weeks, not months or years. Invasive squamous cell carcinomas developed in normal adult, immune-competent mice as soon as 2 weeks after infection with mouse papillomavi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3487a11b-635f-5bdc-a02f-9e05cb2ff658
DOI: 10.1101/2024.09.04.611275

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Invasive cancer and spontaneous regression two weeks after papillomavirus infectionDOI 10.1101/2024.09.04.611275Read

Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancerSemantic proximity Read

Immune Status, Strain Background, and Anatomic Site of Inoculation Affect Mouse Papillomavirus (MmuPV1) Induction of Exophytic Papillomas or Endophytic TrichoblastomasSemantic proximity Read

Investigating early lesion formation following papillomavirus infection using a mouse model and cell cultureSemantic proximity Read

Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor RegressionSemantic proximity Read

Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage.Semantic proximity Read

A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive TractSemantic proximity Read

Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 InfectionSemantic proximity Read

Mus musculus Papillomavirus 1: a New Frontier in Animal Models of Papillomavirus PathogenesisSemantic proximity Read

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancerSemantic proximity Read

The mouse papillomavirus epigenetic signature is characterised by DNA hypermethylation after lesion regressionSemantic proximity Read

The full transcription map of mouse papillomavirus type 1 (MmuPV1) in mouse wart tissuesSemantic proximity Read

Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1).Semantic proximity Read