Article

Single-cell RNA sequencing clarifies dermal fibroblast subset representation <i>in vitro</i> and reveals variable persistence of keloid disease-associated features

2025-08-13

Abstract excerpt

<h4>ABSTRACT</h4> In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true for keloids, the example of pathological scarring exploited in this study, as there is no animal model. Our emerging appreciation of fibroblast heterogeneity from single cell RNA sequencing (scRNA-...

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Literature Corpus work: 34232f60-2511-5774-9b99-e897cc6b618c
DOI: 10.1101/2025.08.11.668109

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