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Article

The Popeye Domain Containing Genes and Their Function as cAMP Effector Proteins in Striated Muscle

13 Mar 2018

Abstract excerpt

The Popeye domain containing (POPDC) genes encode transmembrane proteins, which are abundantly expressed in striated muscle cells. Hallmarks of the POPDC proteins are the presence of three transmembrane domains and the Popeye domain, which makes up a large part of the cytoplasmic portion of the protein and functions as a cAMP-binding domain. Interestingly, despite the prediction of structural similarity between...

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PMID: 29534001
DOI: 10.3390/jcdd5010018

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