Article

Quantifying shared and unique gene content across 17 microbial ecosystems

2022-07-20

Abstract excerpt

Measuring microbial diversity is traditionally based on microbe taxonomy. Here, in contrast, we aimed to quantify heterogeneity in microbial gene content across 14,183 metagenomic samples spanning 17 ecologies including -- 6 human-associated, 7 non-human-host-associated, and 4 in other non-human host environments. In total, we identified 117,629,181 non-redundant genes. The vast majority of genes (66%) occurred in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 33b57a71-c2f6-5b49-b599-2dd36fe526cc
DOI: 10.1101/2022.07.19.500741

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quantifying shared and unique gene content across 17 microbial ecosystemsDOI 10.1101/2022.07.19.500741Read

Proteobacteria drive significant functional variability in the human gut microbiomeSemantic proximity Read

Proteobacteria explain significant functional variability in the human gut microbiome.Semantic proximity Read

Highly divergent ancient gene families in metagenomic samples are compatible with additional divisions of life.Semantic proximity Read

A comprehensive human minimal gut metagenome extends the host’s metabolic potentialSemantic proximity Read

A comprehensive non-redundant gene catalog reveals extensive within-community intraspecies diversity in the human vaginaSemantic proximity Read

Gene-centric metagenomic analyses reveal microbiome functional insights into diseasesSemantic proximity Read

Metagenome-assembled genomes from a population-based cohort uncover novel gut species and within-species diversity, revealing prevalent disease associationsSemantic proximity Read

Comparative Metagenomics Revealed Commonly Enriched Gene Sets in Human Gut MicrobiomesSemantic proximity Read

Inter-individual differences in the gene content of human gut bacterial species.Semantic proximity Read

Metagenome-assembled genomes from a population-based cohort uncover novel gut species and within-species diversity, revealing prevalent disease associations.Semantic proximity Read

[Metagenomics of the intestinal microbiota: potential applications].Semantic proximity Read

VIRGO, a comprehensive non-redundant gene catalog, reveals extensive within community intraspecies diversity in the human vaginaSemantic proximity Read