Article

Comprehensive Assessment of Somatic Copy Number Variation Calling Using Next-Generation Sequencing Data

2021-02-22

Abstract excerpt

Copy number variation (CNV) is a common type of mutation that often drives cancer progression. With advances in next-generation sequencing (NGS), CNVs can be detected in a detailed manner via newly developed computational tools but quality of such CNV calls has not been carefully evaluated. We analyzed CNV calls reported by 6 cutting-edge callers for 91 samples which were derived from the same cancer cell line, pr...

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Literature Corpus work: 337d4812-c1da-5120-b165-1de9ecc9f458
DOI: 10.1101/2021.02.18.431906

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