Article

miRNA-mRNA network analysis identifies PAX5 as a potential regulator of adaptive immune response in COPD

2025-05-07

Abstract excerpt

Micro-ribonucleic acids (miRNAs) are key post-transcriptional regulators of the immune system and may play a role in Chronic Obstructive Pulmonary Disease (COPD). In this paper, we constructed subject-specific miRNA-mRNA regulatory networks using bulk and deconvoluted whole blood RNA-sequencing, whole blood miRNA-sequencing, and B-cell receptor-sequencing data from up to 570 miRNAs, 11,859 mRNAs, and 3,190 partici...

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Identifiers and source

Literature Corpus work: 33697754-a8e5-57b8-bf61-feffc5e0633d
DOI: 10.1101/2025.05.06.651484

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