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Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology

2023-12-23

Abstract excerpt

PIEZO1 is critical to numerous physiological processes, transducing diverse mechanical stimuli into electrical and chemical signals. Recent studies underscore the importance of visualizing endogenous PIEZO1 activity and localization to understand its functional roles. To enable physiologically and clinically relevant studies on human PIEZO1, we genetically engineered human induced pluripotent stem cells (hiPSCs) t...

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Identifiers and source

Literature Corpus work
335fda76-fc9a-5c62-bf1e-005befff38ab
DOI
10.1101/2023.12.22.573117
Open publication

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Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag TechnologyDOI 10.1101/2023.12.22.573117
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