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Piezo in the eye: expression, distribution and roles in ocular diseases

12 Aug 2025

Abstract excerpt

Piezo channels are currently known to be the most sensitive molecular mechanoreceptors. Piezo can respond to membrane tension, sag, shear force, tensile and other mechanical stimuli, produces fast inactivation, small conductance, and low threshold current. In eukaryotic cells, Piezo has two family members: Piezo1 and Piezo2. Functionally, Piezo1 detects whole-membrane tension changes, including swelling and...

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PMID: 40873759
DOI: 10.3389/fphys.2025.1651258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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