Article

Performance comparison: exome-sequencing as a single test replacing Sanger-sequencing

2020-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Systematic performance comparing the results of exome-sequencing as a single test replacing Sanger-sequencing of targeted gene(s) is still lacking. In this study we compared Sanger-sequencing results of 258 genes to those obtained from next generation sequencing (NGS) using two exome-sequencing enrichment kits: Agilent-SureSelectQXT and Illumina-Nextera. Sequencing was performed on leukocytes an...

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Literature Corpus work: 3356649d-6de3-57d0-9afc-6721a6566d68
DOI: 10.1101/2020.11.29.400853

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