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Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma

2023-03-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background：</bold>Clear cell renal cell carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy and is correlated with metabolic reprogramming for adaptation to the tumor microenvironment comprising infiltrated immune cells and immunomodulatory molecules. The role of immune cells in the tumor microenvironment (TME) and their association with abnormal fat...

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Literature Corpus work
287a6d4f-7fd5-5cbf-b8ac-fa71f515e503
DOI
10.21203/rs.3.rs-2634233/v1
Open publication

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