Article

Status epilepticus induces chronic silencing of burster and dominance of regular firing neurons during sharp wave-ripples in the mouse subiculum

2022-05-14

Abstract excerpt

Sharp wave-ripples (SWRs) are hippocampal oscillations associated with memory consolidation. The subiculum, as the hippocampal output structure, ensures that hippocampal memory representations are transferred correctly to the consolidating neocortical regions. Because patients with temporal lobe epilepsy often develop memory deficits, we hypothesized that epileptic networks may disrupt subicular SWRs. We therefore...

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Identifiers and source

Literature Corpus work: 3325428d-91d2-5870-8354-7576b4ab5d44
DOI: 10.1101/2022.05.13.491697

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