Article

Sleep ripples drive single-neuron reactivation for human memory consolidation

2026-03-31

Abstract excerpt

Sleep transforms fragile experiences into lasting memories, but the neuronal basis of this process in humans has remained elusive. In rodents, hippocampal ripples orchestrate the replay of place cell sequences, establishing a cellular mechanism for consolidation – though with limited generalizability to human memory. In humans, neuroimaging has revealed large-scale offline reactivation, but these coarse signals le...

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Literature Corpus work: 98c71f06-1e2b-56f2-9128-652f2322ab64
DOI: 10.64898/2026.03.27.714528

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