Article

Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development

2023-05-25

Abstract excerpt

<h4>Summary</h4> Compared with lowlander migrants, native Tibetans have a higher reproductive success at high altitude though the underlying mechanism remains unclear. Here, we compared the transcriptome and histology of full-term placentas between native Tibetans and Han migrants. We found that the placental trophoblast shows the largest expression divergence between Tibetans and Han, and Tibetans show decreased...

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Literature Corpus work: 32f2dfcd-8152-5f21-aa8b-8b4be6c249cc
DOI: 10.1101/2023.05.24.542081

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