The natural history of Becker muscular dystrophy: A systematic literature review.

Abstract excerpt

BACKGROUND: Becker muscular dystrophy (BMD) is caused primarily by in-frame mutations in the DMD gene. Phenotype varies from asymptomatic to severe; manifestations may include muscle weakness, scoliosis, cardiac involvement, loss of ambulation, respiratory impairment, cognitive dysfunction, and premature death. This study aimed to characterize the frequency and age at occurrence of these milestones. METHODS: A...

Topics

• Humans
• Muscular Dystrophy, Duchenne
• Disease Progression
• Phenotype
• Age of Onset
• Muscle Weakness