Article

Warfarin pharmacogenes do not modify the risk association between warfarin use and cancer mortality among men with prostate cancer

2022-12-15

Abstract excerpt

Although platelets and thrombosis play a role in cancer progression, anticoagulant drug warfarin has not been independently associated with prostate cancer (PCa) survival. SNPs altering warfarin metabolism may in theory affect the association. We investigated the risk associations by warfarin use stratified by the SNP-profile of CYP2C9 and VKORC1 enzymes known to affect warfarin metabolism. A total of 3,241 men pa...

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Identifiers and source

Literature Corpus work: 32cc91fb-13c7-5199-8128-7f13bc7f8ad6
DOI: 10.21203/rs.3.rs-2353582/v1

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