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Article

AI-guided discovery of the invariant host response to viral pandemics

2020-09-22

Abstract excerpt

<h4>ABSTRACT</h4> We sought to define the host immune response, a.k.a, the “cytokine storm” that has been implicated in fatal COVID-19 using an AI-based approach. Over 45,000 transcriptomic datasets of viral pandemics were analyzed to extract a 166-gene signature using ACE2 as a ‘seed’ gene; ACE2 was rationalized because it encodes the receptor that facilitates the entry of SARS-CoV-2 (the virus that causes COVID...

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Literature Corpus work
4e7e6789-0074-5c89-9b54-626a27411174
DOI
10.1101/2020.09.21.305698
Open publication

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AI-guided discovery of the invariant host response to viral pandemicsDOI 10.1101/2020.09.21.305698
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