Article

SOD2 Expression in Patients with Triple-Negative Breast Cancer is Associated with Tumor-infiltrating Lymphocytes and Prognosis

2025-06-10

Abstract excerpt

<title>Abstract</title> <p>Purpose Superoxide dismutase 2 (SOD2), an antioxidant enzyme, plays a pivotal role in carcinogenesis and immune regulation. In this study, we investigated the expression and implications of superoxide dismutase (SOD2) in triple-negative breast cancer (TNBC), an aggressive subtype with varying immune profiles and clinical outcomes. Methods Multiple TNBC cohorts were analyzed with vario...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 32ae3b75-9c29-5d26-951d-6303bb7145bc
DOI: 10.21203/rs.3.rs-6815713/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SOD2 Expression in Patients with Triple-Negative Breast Cancer is Associated with Tumor-infiltrating Lymphocytes and PrognosisDOI 10.21203/rs.3.rs-6815713/v1Read

FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6Semantic proximity Read

Oxidative stress genes define two subtypes of triple-negative breast cancer with prognostic and therapeutic implicationsSemantic proximity Read

Abundance of mitochondrial superoxide dismutase is a negative predictive biomarker for endometriosis-associated ovarian cancersSemantic proximity Read

Lysine-Specific Demethylase 1 (LSD1) Modulates Hypoxia and Antitumor Immunity Pathways in Triple Negative Breast CancerSemantic proximity Read

Prognostic Significance of SQSTM1 in Breast Cancer: A Comprehensive AnalysisSemantic proximity Read

Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response and worse survival in breast cancerSemantic proximity Read

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcomeSemantic proximity Read

Variants rs2758346, rs5746094, and rs2758331 of SOD2 gene: association study with breast cancer in a Mexican population and their analysis in silico.Semantic proximity Read

Genetic polymorphisms and protein expression of NRF2 and Sulfiredoxin predict survival outcomes in breast cancer.Semantic proximity Read

ERO1α as a potential drug target for breast cancer: a systematic review of current evidenceSemantic proximity Read

Metallothionein 2A expression and its relation to different clinical stages and grades of breast cancer in Egyptian patients.Semantic proximity Read