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LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer by facilitating the binding of PCBP1 with MCM3

2024-04-17

Abstract excerpt

<title>Abstract</title> <p>5-Fluorouracil (5-FU) resistance has always been a formidable obstacle in the adjuvant treatment of advanced colorectal cancer (CRC), significantly compromising the patients’ prognosis. In recent years, long non-coding RNAs (lncRNAs) have emerged as key regulators in various pathophysiological processes, particularly in cancers. However, the precise molecular mechanisms governed by thes...

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Literature Corpus work
32aad373-ae13-5dcb-a5b4-98ba990dbf91
DOI
10.21203/rs.3.rs-3866944/v1
Open publication

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