Article
Single-Cell Transcriptomic Attributes and Unbiased Computational Modeling for the Prediction of Immunomodulatory Potency of Mesenchymal Stromal Cells
2020-09-12
Abstract excerpt
<h4>ABSTRACT</h4> Mesenchymal stromal cells (MSCs) are currently being tested in numerous clinical trials as potential cell therapies for the treatment of various diseases and due to their potential immunomodulatory, pro-angiogenic, and regenerative properties. However, variabilities in tissue sources, donors, and manufacturing processes and the lack of defined critical quality attributes (CQAs) and clinically re...
Topics
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- Electrospun Nanofibers in Biomedical Applications
- Extracellular vesicles in disease
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Osteoarthritis Treatment and Mechanisms
- Periodontal Regeneration and Treatments
- Single-cell and spatial transcriptomics
- Tissue Engineering and Regenerative Medicine
Identifiers and source
- Literature Corpus work
- 32913530-4e43-5845-99f4-240a4bc46f76
- DOI
- 10.1101/2020.09.12.294850
