Article

Machine Learning-Driven Glycoproteomic Profiling Identifies Novel Diabetes-Associated Glycosylation Biomarkers

2025-02-26

Abstract excerpt

Glycosylation plays a critical role in protein function and disease progression, including diabetes mellitus. This study performed a comprehensive glycoproteomic analysis comparing healthy volunteers (HV) and DM samples, identifying 19,374 peptides and 2,113 proteins, of which 1,104 were glycosylated. A total of 287 distinct glycans were mapped to 3,722 glycosylated peptides, revealing significant differences in g...

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Literature Corpus work: 32368ce0-6640-568d-9bfc-5db3a449ffd7
DOI: 10.1101/2025.02.24.25322514

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