Article
Head-to-head comparison of aptamer- and antibody-based proteomic platforms in human cerebrospinal fluid samples from a real-world memory clinic cohort
2024-07-18
Abstract excerpt
High-throughput proteomic platforms have a crucial role in identifying novel Alzheimer’s disease (AD) biomarkers and pathways. In this study, we evaluated the reproducibility and reliability of aptamer-based (SomaScan® 7k) and antibody-based (Olink® Explore 3k) proteomic platforms in cerebrospinal fluid (CSF) samples from the Ace Alzheimer Center Barcelona real-world cohort. Intra- and interplatform reproducibilit...
Topics
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- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Bioinformatics and Genomic Networks
- Metabolomics and Mass Spectrometry Studies
- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
- S100 Proteins and Annexins
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 31ff98d5-68b4-5aa2-888a-0e572b37129e
- DOI
- 10.1101/2024.07.18.24310563
