Article

Dimethyl sulfoxide primes induced pluripotent stem cells for more efficient nephron progenitor and kidney organoid differentiation

2025-02-08

Abstract excerpt

The field of human induced pluripotent stem cells (hiPSCs) has seen significant progress since the discovery of reprogramming somatic cells using the transcription factors Oct4, Sox2, Klf4, and c-Myc. hiPSCs are similar to embryonic stem cells in a primed state of pluripotency and has the potential to differentiate into any adult human cell type, offering a versatile tool for research and potential therapeutic app...

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Literature Corpus work: 31f7defe-d2ff-50e5-82e6-829f1aa928c9
DOI: 10.1101/2025.02.07.637033

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