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A three dimensional human immune-tumor cell model reveals the importance of isotypes in antibody-based immunotherapy

2020-07-02

Abstract excerpt

Monoclonal antibodies (mAb) have revolutionized clinical medicine, especially in the field of cancer immunotherapy. The challenge now is to improve the response rates in the patients, as immunotherapy still fails for many patients. Strategies to enhance tumor cell death is a fundamental aim, but relevant model systems for human tumor immunology are lacking. Herein, we have developed a novel pre-clinical human immu...

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Literature Corpus work
31a97506-7d75-598f-afaf-17e686c8b9df
DOI
10.1101/2020.07.01.181800
Open publication

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A three dimensional human immune-tumor cell model reveals the importance of isotypes in antibody-based immunotherapyDOI 10.1101/2020.07.01.181800
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