Article

<i>DIRC3-IGFBP5</i> is a shared genetic risk locus and therapeutic target for carpal tunnel syndrome and trigger finger

2021-10-11

Abstract excerpt

Trigger finger (TF) and carpal tunnel syndrome (CTS) are two common non-traumatic hand disorders that frequently co-occur. By identifying TF and CTS cases in UK Biobank (UKB), we confirmed a highly significant phenotypic association between the diseases. To investigate the genetic basis for this association we performed a genome-wide association study (GWAS) including 2,908 TF cases and 436,579 European controls i...

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Literature Corpus work: 315a695c-e9fa-5a8d-bbef-460bdadc594d
DOI: 10.1101/2021.10.07.21264697

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