Article
Hsa-miR-31-5p controls a metabolic switch in psoriatic keratinocytes that identifies therapeutic intervention
2022-01-22
Abstract excerpt
Psoriasis is characterized by a combination of keratinocyte hyperproliferation and immune cell activation. Immune cell activation requires increased glucose consumption, consequently limiting glucose availability for other cell types like keratinocytes. In psoriasis Hsa-microRNA-31-5p (miR-31) is highly expressed in keratinocytes. Here we show that miR-31 expression in keratinocytes is induced by limited glucose a...
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Identifiers and source
- Literature Corpus work
- 30e19734-95dc-5c01-978f-833852114618
- DOI
- 10.1101/2022.01.21.477183