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Crosstalk among TFEB, the autophagy lysosomal pathway and ROS derived from damaged mitochondria in NaAsO2-induced auditory senescent cells

2023-10-10

Abstract excerpt

<title>Abstract</title> <p>Age-related hearing loss (ARHL) is one of the most prevalent types of sensory decline in a superaging society. Although various studies have focused on the effect of oxidative stress on the inner ear as an inducer of ARHL, there are no effective preventive approaches for ARHL. Recent studies have suggested that oxidative stress-induced DNA damage responses (oxidative DDRs) drive cochlea...

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Literature Corpus work
30c13a9b-be0d-5b98-9706-cca2f359ba08
DOI
10.21203/rs.3.rs-3321782/v1
Open publication

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