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Article

A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma

21 Feb 2023

Abstract excerpt

The efficacy of anti‐angiogenic treatment by targeting VEGF/VEGF receptors in metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. Discovering the reasons behind this variability could lead to the identification of relevant therapeutic targets. Thus, we investigated the novel splice variants of VEGF that are less efficiently inhibited by anti‐VEGF/VEGFR targeting than the...

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PMID: 36810959
DOI: 10.1002/1878-0261.13401

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