Quantification of influenza virus mini viral RNA dynamics using Cas13

Abstract excerpt

Influenza A virus RNA synthesis produces full-length and aberrant RNA molecules, which include defective viral genomes (DVG) and mini viral RNAs (mvRNA). Sequencing approaches have shown that aberrant RNA species may be present during infection, and that they can vary in size, segment origin, and sequence. Moreover, a subset of aberrant RNA molecules can bind and activate host pathogen receptor retinoic acid-induc...

Topics

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• Animal Disease Management and Epidemiology
• Bacteriophages and microbial interactions
• CRISPR and Genetic Engineering
• Influenza Virus Research Studies
• interferon and immune responses
• Mosquito-borne diseases and control
• Respiratory viral infections research
• RNA and protein synthesis mechanisms

Identifiers and source

Literature Corpus work

30b49797-bebe-5bd9-be02-1c85a509473d

DOI

10.1101/2023.11.03.565460