Article

A hierarchical genotyping framework using DNA melting temperatures applied to adenovirus species typing

2022-03-01

Abstract excerpt

Known genetic variation for a pathogen, in conjunction with post-PCR melting curve analysis, can be leveraged to provide increased taxonomic detail for pathogen identification in commercial molecular diagnostic tests. The increased taxonomic detail may be used by clinicians and public health decision makers to observe circulation patterns, monitor for outbreaks, and inform local testing practices. We propose a met...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 30b0fac1-6f19-51d1-8d0d-17d93da106a8
DOI: 10.1101/2022.02.28.482221

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A hierarchical genotyping framework using DNA melting temperatures applied to adenovirus species typingDOI 10.1101/2022.02.28.482221Read

A Hierarchical Genotyping Framework Using DNA Melting Temperatures Applied to Adenovirus Species Typing.Semantic proximity Read

Development and clinical validation of a novel multiplex PCR test for detection of respiratory pathogens via fluorescence melting curve analysisSemantic proximity Read

AYUKA: A toolkit for fast viral genotyping using whole genome sequencingSemantic proximity Read

Trainable high resolution melt curve machine learning classifier for large-scale reliable genotyping of sequence variants.Semantic proximity Read

Melting curve analysis reveals false-positive norovirus detection in a molecular syndromic panelSemantic proximity Read

Machine learning based DNA melt curve profiling enables automated novel genotype detection.Semantic proximity Read

Evaluation of two commercial human adenovirus typing kits in children with acute respiratory tract infection.Semantic proximity Read

A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutationsSemantic proximity Read

A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations.Semantic proximity Read

Identification of Bacterial Coinfection in SARS-CoV-2 Infected patients, by High Resolution MeltingSemantic proximity Read

Species-Specific Identification of Human Adenoviruses by a Multiplex PCR AssaySemantic proximity Read

Software application profile: MeltingPlot, a user-friendly online tool for epidemiological investigation using High Resolution Melting dataSemantic proximity Read