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Article

A Hierarchical Genotyping Framework Using DNA Melting Temperatures Applied to Adenovirus Species Typing.

International journal of molecular sciences - 13 May 2022

Galvin Ben, Jones Jay, Powell Michaela, Olin Katherine, Jones Matthew, Robbins Thomas

Abstract excerpt

Known genetic variation, in conjunction with post-PCR melting curve analysis, can be leveraged to provide increased taxonomic detail for pathogen identification in commercial molecular diagnostic tests. Increased taxonomic detail may be used by clinicians and public health decision-makers to observe circulation patterns, monitor for outbreaks, and inform testing practices. We propose a method for expanding the...

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Identifiers

PMID: 35628251
DOI: 10.3390/ijms23105441
PMCID: PMC9141461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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