Article
Human Gene and Microbial Analyses Suggest Immunotherapy-like Mechanisms in Complete Response to Radiotherapy in Rectal Cancer
2022-07-09
Abstract excerpt
The treatment of rectal cancer usually involves total mesorectal excision, with preoperative chemoradiotherapy (CRT) that is aimed at downstaging tumors before surgical procedure. CRT response varies, with some patients completely responding to CRT and negating the need for surgery, and some patients not responding to the treatment at all. Identifying biomarkers of response to CRT would be beneficial in identifyin...
Topics
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- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Epigenetics and DNA Methylation
- Genetic factors in colorectal cancer
- Gut microbiota and health
- Inflammatory Biomarkers in Disease Prognosis
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
Identifiers and source
- Literature Corpus work
- 308d3bfc-2685-556c-9333-f24aa1195ed5
- DOI
- 10.1101/2022.07.07.22277387
