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geneshot: gene-level metagenomics identifies genome islands associated with immunotherapy response

5 May 2021

Abstract excerpt

Researchers must be able to generate experimentally testable hypotheses from sequencing-based observational microbiome experiments to discover the mechanisms underlying the influence of gut microbes on human health. We describe geneshot, a novel bioinformatics tool for identifying testable hypotheses based on gene-level metagenomic analysis of WGS microbiome data. By applying geneshot to two independent...

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PMID: 33952321
DOI: 10.1186/s13059-021-02355-6

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