Exome and Tissue-Associated Microbiota as Predictive Markers of Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer

Abstract excerpt

The clinical and pathological responses to multimodal neoadjuvant therapy in locally advanced rectal cancers (LARCs) remain unpredictable, and robust biomarkers are still lacking. Recent studies have shown that tumors present somatic molecular alterations related to better treatment response, and it is also clear that tumor-associated bacteria are modulators of chemotherapy and immunotherapy efficacy, therefore...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Colorectal Cancer Screening and Detection
• Share to Colorectal Cancer Surgical Treatments
• Share to Genetic factors in colorectal cancer