Evaluation of Humoral and Cellular Immune Responses to the SARS-CoV-2 Vaccine in Patients With Common Variable Immunodeficiency Phenotype and Patient Receiving B-Cell Depletion Therapy.

doi:10.3389/fimmu.2022.895209

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Evaluation of Humoral and Cellular Immune Responses to the SARS-CoV-2 Vaccine in Patients With Common Variable Immunodeficiency Phenotype and Patient Receiving B-Cell Depletion Therapy.

Frontiers in immunology - 1 Jan 2022

Antolí Arnau, Rocamora-Blanch Gemma, Framil Mario, Mas-Bosch Virgínia, Navarro Sergio, Bermudez Carla, Martinez-Yelamos Sergio, Dopico Eva, Calatayud Laura, Garcia-Muñoz Nadia, Hernández-Benítez Luis Humberto, Riera-Mestre Antoni, Bas Jordi, Masuet-Aumatell Cristina, Rigo-Bonnin Raúl, Morandeira Francisco, Solanich Xavier

Abstract excerpt

Introduction: SARS-CoV-2 vaccines' effectiveness is not yet clearly known in immunocompromised patients. This study aims to assess the humoral and cellular specific immune response to SARS-CoV-2 vaccines and the predictors of poor response in patients with common variable immunodeficiency (CVID) phenotype and in patients treated with B-cell depletion therapies (BCDT), as well as the safety of these vaccines....

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Identifiers

PMID: 35572562
DOI: 10.3389/fimmu.2022.895209
PMCID: PMC9098934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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