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Article

Role of antiviral CD8+ T cell immunity to SARS-CoV-2 infection and vaccination

3 Mar 2025

Abstract excerpt

The COVID-19 pandemic has greatly enhanced our understanding of CD8+ T cell immunity and their role in natural infection and vaccine-induced protection. Rapid and early SARS-CoV-2-specific CD8+ T cell responses have been associated with efficient viral clearance and mild disease. Virus-specific CD8+ T cell responses can compensate for waning, morbidity-related, and iatrogenic reduction of humoral immunity. After...

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PMID: 40029063
DOI: 10.1128/jvi.01350-24

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